Monitoring of the Parasite Load in the Digestive Tract of Rhodnius prolixus by Combined qPCR Analysis and Imaging Techniques Provides New Insights into the Trypanosome Life Cycle.

Here we report the monitoring of the digestive tract colonization of Rhodnius prolixus by Trypanosoma cruzi using an accurate determination of the parasite load by qPCR coupled with fluorescence and bioluminescence imaging (BLI).These complementary methods revealed critical steps necessary for the parasite Ammonia Removers population to colonize th

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Deregulation of Interferon Signaling in Malignant Cells

Interferons (IFNs) are a family of cytokines with potent BOOKS antiproliferative, antiviral, and immunomodulatory properties.Much has been learned about IFNs and IFN-activated signaling cascades over the last 50 years.Due to their potent antitumor effects in vitro and in vivo, recombinant IFNs have been used extensively over the years, alone or in

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Cranial Anatomy and Palaeoneurology of the Archosaur Riojasuchus tenuisceps from the Los Colorados Formation, La Rioja, Argentina.

Riojasuchus tenuisceps Bonaparte 1967 is currently known from four specimens, including two complete skulls, collected in the late 1960s from the upper levels of the Los Colorados Formation (Late Triassic), La Rioja, Argentina.Computed tomography BOOKS (CT) scans of the skulls of the holotype and a referred specimen of Riojasuchus tenuisceps and th

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